Aerio™ Auto-Injector Platform

Discover the precision and adaptability of the Aerio Auto-Injector Platform, our proprietary drug delivery system designed to meet the highest standards of device function and form.

Developed by Patients, For Patients™

Aerio auto-injectors are designed to be compact, portable devices that are easy-to-use. The Aerio Auto-Injector Platform uses proprietary technology that enables delivery of larger volume and higher viscosity formulations and controls injection flow rates. The Aerio auto-injector is available in three different versions: single container, dual container, and dual chamber.

Single Container
Auto-Injector

Dual Chamber
Auto-Injector

Dual Container
Auto-Injector

Drug Delivery Capability

Automatic delivery of single dose, up to 10 mL

Automatic, simultaneous delivery of two doses, up to 10 mL each

Automatic delivery of lyophilized product OR Two different liquids

Container Count

Single Container

Two Containers (two separate injections)

One Container, Dual Chamber (bypass)

Maximum Volume Delivered

10 mL

20 mL

5 mL

Viscosity

1cP – 2,000 cP

1 cP – 2,000 cP

Container Type

Cartridge OR Pre-filled syringe

Automatic mixing and administration using off-the-shelf bypass cartridge

Gas Powered, Non-Coaxial Design

Two-Step Activation

Rapid Automatic Needle Insertion and Retraction

Electronic Voice Guidance

Visual Cues

Needle Gauge

18g – 29g

Features of the Aerio Auto-Injector Platform

Through diligent Human Factors Engineering and fully automated manufacturing, we optimize and validate the usability of every Aerio-enabled device.

Electronic Trainer

Training device with voice guidance and visual prompts

Connected Health

Bluetooth capability to communicate use related information/data

Custom Form Factor

Design enabled form factor flexibility

Drug Flow Regulation

Manage drug flow velocity for dose volumes ranging from 0.1 to 20 mL

Formulation Flexibility

Deliver wet + dry and/or wet + wet solutions that supports simultaneous drug administration

Environmental Adaptability

Drug delivery in extreme temperatures, humidities, altitudes, and more challenging environments

Developed By Patients, For Patients™

At Kaléo, we take a forward-thinking approach when developing products and solutions that will meet the needs of patients and our partners.

Product Innovation

We take our commitment to the needs of patients, their families and caregivers very seriously. The meticulous approach we bring to every stage of development is driven by a focus on each patient’s need to administer medicines with comfort and precision. We are proud of our ~ 200 issued patents for our products and are driven by the impact our products have on people’s lives.

Human Factors Engineering

Our Human Factors Engineering ensures patient needs inform our product design. Real-world use and performance is our priority and includes testing simulation scenarios that mimic diverse environments and conditions for patients, families and military, such as:

• Extreme temperature conditions
• Low-light settings
• High-pressure situations
• Scenarios in which users have limited dexterity

Manufacturing & Quality

Kaléo is committed to the highest standards of product and manufacturing quality. Final manufacturing and assembly of our products is conducted in the United States on a 100% automated robotic production line with more than 100 quality checks on every device.

Kaléo has redefined expectations in drug-delivery technology having met the U.S. Food and Drug Administration (FDA) draft guidance standard for 99.999% device reliability. And, with more than 12 million auto-injectors manufactured, patients and partners are assured that we design quality into our products and precision into every aspect of the manufacturing process.

Intellectual Property

Kaléo auto-injection technologies are protected by an extensive intellectual property portfolio of ~ 200 issued patents.

IP PORTFOLIO

~200

Patents Issued

U.S. Issued Patents

DESIGN

Form Factor
Human Factors Engineering

Device Functionality
Gas powered, non-coaxial

Drug Formulation & Container
Prefilled Syringe vs. Cartridge

Electronic Solutions
Audio & Visual Prompts